Zoonotic Bacteria Persistence and Susceptibility
- Infectious disease
Abstract
Hypermucoviscous K. pneumoniae (HMV) are emergent zoonotic pathogens associated with increased invasiveness and pathogenicity in terrestrial and marine mammals. In this study, HMV and non-HMV isolates recovered from stranded pinnipeds were used to investigate: 1) their persistence in sea and fresh water microcosms at 10 and 20°C, 2) their capacity to form biofilms, and 3) the biocide efficacy of four disinfectants on their planktonic and biofilm phenotypes. Results indicated that although HMV isolates were significantly more mucoviscous, non-HMV isolates displayed significantly greater capacity to form biofilms (p < 0.05). Additionally, non-HMV isolates persisted in greater numbers in both sea- and freshwater, particularly at 20°C. These two phenomena could be associated with the greater growth observed for non-HMV isolates in in-vitro growth-curve assays (p < 0.05). Similar susceptibility to disinfectants was detected in HMV and non-HMV isolates when exposed for 24 h; however, the minimal biofilm disinfectant eradication concentration for HMV isolates was significantly higher than that for non-HMV when exposed to disinfectants for 0.5 h. This information should be taken into consideration when developing biosecurity protocols in facilities holding marine mammals in captivity.
Soto, E., Abdelrazek, S.M., Basbas, C., Duignan, P.J., Rios, C. and Byrne, B.A., 2020. Environmental persistence and disinfectant susceptibility of Klebsiella pneumoniae recovered from pinnipeds stranded on the California Coast. Veterinary Microbiology, 241, pp.108554.
Pádraig Duignan
Carlos Rios
Meet The Experts
{"image":"\/People\/Portrait\/cropped-images\/Padraig Duignan-0-56-635-496-1601760621.jpg","alt":"Padraig Duignan","title":"P\u00e1draig Duignan","text":"Director of Pathology","link_url":"https:\/\/www.marinemammalcenter.org\/person\/padraig-duignan","link_text":"Read Bio"}
{"image":"\/People\/Portrait\/cropped-images\/carlos-rios-0-180-1160-906-1605722153.jpg","alt":"Carlos Rios","title":"Carlos Rios","text":"Clinical Laboratory Senior Manager","link_url":"https:\/\/www.marinemammalcenter.org\/person\/carlos-rios","link_text":"Read Bio"}
Related Publications
{"image":"\/Animals\/Wild\/Other species\/nz-sea-lion-shutterstock.jpg","alt":"New Zealand sea lion","title":"Causes of Death in Two Populations of New Zealand Sea Lions","link_url":"https:\/\/www.marinemammalcenter.org\/publications\/causes-of-death-in-two-populations-of-new-zealand-sea-lions","label":"Research Paper"}
{"image":"\/Animals\/Patients\/California sea lions\/cropped-images\/csl-photo-by-bill-hunnewell-c-the-marine-mammal-center-1-0-0-2358-1722-1600891644.jpg","alt":"California sea lions","title":"Emerging Viruses in Marine Mammals","link_url":"https:\/\/www.marinemammalcenter.org\/publications\/emerging-viruses-in-marine-mammals","label":"Research Paper"}
{"image":"\/Animals\/Patients\/California sea lions\/csl-photo-by-bill-hunnewell-c-the-marine-mammal-center-12.jpg","alt":"two California sea lions","title":"Multi-Phase Muscle Breakdown in California Sea Lions","link_url":"https:\/\/www.marinemammalcenter.org\/publications\/multi-phase-muscle-breakdown-in-california-sea-lions","label":"Research Paper"}
{"image":"\/Animals\/Wild\/Other species\/nz-sea-lion-shutterstock.jpg","alt":"New Zealand sea lion","title":"Tuberculosis in New Zealand Seals, Sea Lions and Dolphins","link_url":"https:\/\/www.marinemammalcenter.org\/publications\/tuberculosis-in-new-zealand-seals-sea-lions-and-dolphins","label":"Research Paper"}
Recent News
{"image":"\/Animals\/Wild\/Other species\/cropped-images\/two-seals-playing-shutterstock-250-0-3211-2510-1602631793.jpg","alt":"two seals playing on a beach","title":"Meaningful Father\u2019s Day Gifts for Ocean Lovers","link_url":"https:\/\/www.marinemammalcenter.org\/news\/eco-friendly-fathers-day-gifts-that-give-back","label":"News Update","date":"2025-05-09 12:37:57"}
{"image":"\/People\/Action\/Veterinary care\/cropped-images\/cara-field-hs-eye-exam-by-elena-graham-c-the-marine-mammal-center-117-0-1270-992-1746828532.jpg","alt":"Dr. Cara Field performs an exam on a harbor seal pup","title":"Marketplace: Diving below the surface with an aquatic veterinarian","link_url":"https:\/\/www.marinemammalcenter.org\/news\/marketplace-diving-below-the-surface-with-an-aquatic-veterinarian","label":"In the News","date":"2025-05-05 02:00:00"}
Marketplace: Diving below the surface with an aquatic veterinarian
May 5, 2025
Read More{"image":"\/Animals\/Patients\/Elephant seals\/cropped-images\/es-duo-in-pool-by-bill-hunnewell-c-the-marine-mammal-center-80-0-1270-992-1746831113.jpg","alt":"two elephant seal pups in a pool","title":"But Why: What\u2019s a seal? What\u2019s a sea lion?","link_url":"https:\/\/www.marinemammalcenter.org\/news\/but-why-whats-a-seal-whats-a-sea-lion","label":"In the News","date":"2025-05-02 02:00:00"}
{"image":"\/Animals\/Wild\/California sea lion\/cropped-images\/csl-release-4-5-24photo-by-chris-deimler-c-the-marine-mammal-center-138-0-1270-992-1745348188.jpg","alt":"Four young California sea lions walk on the beach toward the ocean.","title":"Achievements in Ocean Health","link_url":"https:\/\/www.marinemammalcenter.org\/news\/achievements-in-ocean-health","label":"News Update","date":"2025-04-23 10:20:00"}
